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Single cell lineage reconstruction using distance-based algorithms and the R package, DCLEAR
BACKGROUND: DCLEAR is an R package used for single cell lineage reconstruction. The advances of CRISPR-based gene editing technologies have enabled the prediction of cell lineage trees based on observed edited barcodes from each cell. However, the performance of existing reconstruction methods of ce...
Autores principales: | Gong, Wuming, Kim, Hyunwoo J., Garry, Daniel J., Kwak, Il-Youp |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944039/ https://www.ncbi.nlm.nih.gov/pubmed/35331133 http://dx.doi.org/10.1186/s12859-022-04633-x |
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