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A system for multiplexed selection of aptamers with exquisite specificity without counterselection

Aptamers have proven to be valuable tools for the detection of small molecules due to their remarkable ability to specifically discriminate between structurally similar molecules. Most aptamer selection efforts have relied on counterselection to eliminate aptamers that exhibit unwanted cross-reactiv...

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Detalles Bibliográficos
Autores principales: Yoshikawa, Alex M., Wan, Leighton, Zheng, Liwei, Eisenstein, Michael, Soh, H. Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944265/
https://www.ncbi.nlm.nih.gov/pubmed/35290115
http://dx.doi.org/10.1073/pnas.2119945119