pH-degradable, bisphosphonate-loaded nanogels attenuate liver fibrosis by repolarization of M2-type macrophages

Immune-suppressive (M2-type) macrophages can contribute to the progression of cancer and fibrosis. In chronic liver diseases, M2-type macrophages promote the replacement of functional parenchyma by collagen-rich scar tissue. Here, we aim to prevent liver fibrosis progression by repolarizing liver M2...

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Detalles Bibliográficos
Autores principales: Kaps, Leonard, Huppertsberg, Anne, Choteschovsky, Niklas, Klefenz, Adrian, Durak, Feyza, Schrörs, Babara, Diken, Mustafa, Eichler, Emma, Rosigkeit, Sebastian, Schmitt, Sascha, Leps, Christian, Schulze, Alicia, Foerster, Friedrich, Bockamp, Ernesto, De Geest, Bruno G., Koynov, Kaloian, Räder, Hans-Joachim, Tenzer, Stefan, Marini, Federico, Schuppan, Detlef, Nuhn, Lutz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Physical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944276/
https://www.ncbi.nlm.nih.gov/pubmed/35290110
http://dx.doi.org/10.1073/pnas.2122310119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944276/
https://www.ncbi.nlm.nih.gov/pubmed/35290110
http://dx.doi.org/10.1073/pnas.2122310119

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