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Ionizing radiation alters organoid forming potential and replenishment rate in a dose/dose-rate dependent manner

Intestinal organoids are an in vitro cultured tissue model generated from intestinal stem cells, and they contain a mixture of epithelial cell types. We previously established an efficient ‘one cell/well’ sorting method, and defined organoid-forming potential (OFP) as a useful index to evaluate the...

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Detalles Bibliográficos
Autores principales: Fujimichi, Yuki, Otsuka, Kensuke, Tomita, Masanori, Iwasaki, Toshiyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944312/
https://www.ncbi.nlm.nih.gov/pubmed/34977948
http://dx.doi.org/10.1093/jrr/rrab120