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Nicaraven mitigates radiation-induced lung injury by downregulating the NF-κB and TGF-β/Smad pathways to suppress the inflammatory response

Radiation-induced lung injury (RILI) is commonly observed in patients receiving radiotherapy, and clinical prevention and treatment remain difficult. We investigated the effect and mechanism of nicaraven for mitigating RILI. C57BL/6 N mice (12-week-old) were treated daily with 6 Gy X-ray thoracic ra...

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Detalles Bibliográficos
Autores principales: Xu, Yong, Zhai, Da, Goto, Shinji, Zhang, Xu, Jingu, Keiichi, Li, Tao-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944328/
https://www.ncbi.nlm.nih.gov/pubmed/34999842
http://dx.doi.org/10.1093/jrr/rrab112