Cargando…
Nicaraven mitigates radiation-induced lung injury by downregulating the NF-κB and TGF-β/Smad pathways to suppress the inflammatory response
Radiation-induced lung injury (RILI) is commonly observed in patients receiving radiotherapy, and clinical prevention and treatment remain difficult. We investigated the effect and mechanism of nicaraven for mitigating RILI. C57BL/6 N mice (12-week-old) were treated daily with 6 Gy X-ray thoracic ra...
Autores principales: | Xu, Yong, Zhai, Da, Goto, Shinji, Zhang, Xu, Jingu, Keiichi, Li, Tao-Sheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944328/ https://www.ncbi.nlm.nih.gov/pubmed/34999842 http://dx.doi.org/10.1093/jrr/rrab112 |
Ejemplares similares
-
Optimization on the dose and time of nicaraven administration for
mitigating the side effects of radiotherapy in a preclinical tumor-bearing mouse
model
por: Xu, Yong, et al.
Publicado: (2022) -
Regenerative medicine for radiation emergencies
por: Higashi, Yukihito, et al.
Publicado: (2021) -
Nicaraven induces programmed cell death by distinct mechanisms according to the expression levels of Bcl-2 and poly (ADP-ribose) glycohydrolase in cancer cells
por: Abdelghany, Lina, et al.
Publicado: (2022) -
Nicaraven Attenuates Radiation-Induced Injury in Hematopoietic Stem/Progenitor Cells in Mice
por: Kawakatsu, Miho, et al.
Publicado: (2013) -
Lens opacity prevalence among the residents in high natural background radiation area in Yangjiang, China
por: Su, Yinping, et al.
Publicado: (2020)