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Design and Characterization of Novel Antibody-Cytokine Fusion Proteins Based on Interleukin-21

Interleukin-21 (IL21) is a pleiotropic cytokine involved in the modulation of both innate and adaptive immunity. IL21 is mainly secreted by natural killer (NK) and activated CD4+ T-cells. The biology of this cytokine can be associated to proinflammatory responses reflecting its potent stimulatory ac...

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Detalles Bibliográficos
Autores principales: Di Nitto, Cesare, Neri, Dario, Weiss, Tobias, Weller, Michael, De Luca, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944420/
https://www.ncbi.nlm.nih.gov/pubmed/35323193
http://dx.doi.org/10.3390/antib11010019