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Apoptosis-Inducing Factor Deficiency Induces Tissue-Specific Alterations in Autophagy: Insights from a Preclinical Model of Mitochondrial Disease and Exercise Training Effects

We analyzed the effects of apoptosis-inducing factor (AIF) deficiency, as well as those of an exercise training intervention on autophagy across tissues (heart, skeletal muscle, cerebellum and brain), that are primarily affected by mitochondrial diseases, using a preclinical model of these condition...

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Detalles Bibliográficos
Autores principales: Laine-Menéndez, Sara, Fernández-de la Torre, Miguel, Fiuza-Luces, Carmen, Delmiro, Aitor, Arenas, Joaquín, Martín, Miguel Ángel, Boya, Patricia, Lucia, Alejandro, Morán, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944439/
https://www.ncbi.nlm.nih.gov/pubmed/35326160
http://dx.doi.org/10.3390/antiox11030510