Combined Activity of the Redox-Modulating Compound Setanaxib (GKT137831) with Cytotoxic Agents in the Killing of Acute Myeloid Leukemia Cells

Acute myeloid leukemia (AML) cells harbor elevated levels of reactive oxygen species (ROS), which promote cell proliferation and cause oxidative stress. Therefore, the inhibition of ROS formation or elevation beyond a toxic level have been considered as therapeutic strategies. ROS elevation has rece...

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Detalles Bibliográficos
Autores principales: Demircan, Muhammed Burak, Mgbecheta, Peter C., Kresinsky, Anne, Schnoeder, Tina M., Schröder, Katrin, Heidel, Florian H., Böhmer, Frank D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944474/
https://www.ncbi.nlm.nih.gov/pubmed/35326163
http://dx.doi.org/10.3390/antiox11030513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944474/
https://www.ncbi.nlm.nih.gov/pubmed/35326163
http://dx.doi.org/10.3390/antiox11030513

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