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Cholesterol Induces Oxidative Stress, Mitochondrial Damage and Death in Hepatic Stellate Cells to Mitigate Liver Fibrosis in Mice Model of NASH

Liver fibrosis and its end-stage disease cirrhosis are major world health problems arising from chronic injury of the liver. In recent years, the hypothesis that hepatic stellate cells’ (HSCs’) activation and fibrosis can be mitigated by HSC apoptosis and cell death has become of interest. In the cu...

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Detalles Bibliográficos
Autores principales: Rauchbach, Einat, Zeigerman, Haim, Abu-Halaka, Diana, Tirosh, Oren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944482/
https://www.ncbi.nlm.nih.gov/pubmed/35326188
http://dx.doi.org/10.3390/antiox11030536