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Activation of the Nrf2 Pathway Prevents Mitochondrial Dysfunction Induced by Caspase-3 Cleaved Tau: Implications for Alzheimer’s Disease

Alzheimer’s disease (AD) is characterized by memory and cognitive impairment, accompanied by the accumulation of extracellular deposits of amyloid β-peptide (Aβ) and the presence of neurofibrillary tangles (NFTs) composed of pathological forms of tau protein. Mitochondrial dysfunction and oxidative...

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Detalles Bibliográficos
Autores principales: Villavicencio-Tejo, Francisca, Olesen, Margrethe A., Aránguiz, Alejandra, Quintanilla, Rodrigo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944569/
https://www.ncbi.nlm.nih.gov/pubmed/35326165
http://dx.doi.org/10.3390/antiox11030515