Cargando…

Bending-torsional elasticity and energetics of the plus-end microtubule tip

Microtubules (MTs), mesoscopic cellular filaments, grow primarily by the addition of GTP-bound tubulin dimers at their dynamic flaring plus-end tips. They operate as chemomechanical energy transducers with stochastic transitions to an astounding shortening motion upon hydrolyzing GTP to GDP. Time-re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Igaev, Maxim, Grubmüller, Helmut
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944587/ https://www.ncbi.nlm.nih.gov/pubmed/35302883 http://dx.doi.org/10.1073/pnas.2115516119

Ejemplares similares

Microtubule assembly governed by tubulin allosteric gain in flexibility and lattice induced fit
por: Igaev, Maxim, et al.
Publicado: (2018)

Microtubule instability driven by longitudinal and lateral strain propagation
por: Igaev, Maxim, et al.
Publicado: (2020)

Choice of fluorophore affects dynamic DNA nanostructures
por: Jahnke, Kevin, et al.
Publicado: (2021)

Gcap14 is a microtubule plus-end-tracking protein coordinating microtubule–actin crosstalk during neurodevelopment
por: Mun, Dong Jin, et al.
Publicado: (2023)

Molecular mechanism and energetics of coupling between substrate binding and product release in the F(1)-ATPase catalytic cycle
por: Badocha, Michał, et al.
Publicado: (2023)

Automated cryo-EM structure refinement using correlation-driven molecular dynamics
por: Igaev, Maxim, et al.
Publicado: (2019)

Theory of tip structure–dependent microtubule catastrophes and damage-induced microtubule rescues
por: Alexandrova, Veronika V., et al.
Publicado: (2022)

TIP150 interacts with and targets MCAK at the microtubule plus ends
por: Jiang, Kai, et al.
Publicado: (2009)

Kinesin-14 motors participate in a force balance at microtubule plus-ends to regulate dynamic instability
por: Ogren, Allison, et al.
Publicado: (2022)

TIP maker and TIP marker; EB1 as a master controller of microtubule plus ends
por: Vaughan, Kevin T.
Publicado: (2005)

Probing the elastic limit of DNA bending
por: Le, Tung T., et al.
Publicado: (2014)

Remote control of microtubule plus-end dynamics and function from the minus-end
por: Chen, Xiuzhen, et al.
Publicado: (2019)

Some basic problems of the mathematical theory of elasticity: fundamental equations plane theory of elasticity torsion and bending
por: Muskhelishvili, N I
Publicado: (1977)

Some basic problems of the mathematical theory of elasticity: fundamental equations, plane theory of elasticity, torsion and bending
por: Muskhelishvili, N I
Publicado: (1953)

Reconstitution of dynein transport to the microtubule plus end by kinesin
por: Roberts, Anthony J, et al.
Publicado: (2014)

Structural state recognition facilitates tip tracking of EB1 at growing microtubule ends
por: Reid, Taylor A, et al.
Publicado: (2019)

MTB-3, a Microtubule Plus-End Tracking Protein (+TIP) of Neurospora crassa
por: Mouriño-Pérez, Rosa R., et al.
Publicado: (2013)

Opposing kinesin complexes queue at plus tips to ensure microtubule catastrophe at cell ends
por: Meadows, John C, et al.
Publicado: (2018)

Microtubule plus-end dynamics link wound repair to the innate immune response
por: Taffoni, Clara, et al.
Publicado: (2020)

TIPsy tour guides: how microtubule plus-end tracking proteins (+TIPs) facilitate axon guidance
por: Bearce, Elizabeth A., et al.
Publicado: (2015)

DNA sequence and methylation prescribe the inside-out conformational dynamics and bending energetics of DNA minicircles
por: Yoo, Jejoong, et al.
Publicado: (2021)

Microtubule plus-ends act as physical signaling hubs to activate RhoA during cytokinesis
por: Verma, Vikash, et al.
Publicado: (2019)

Cross-linkers at growing microtubule ends generate forces that drive actin transport
por: Alkemade, Celine, et al.
Publicado: (2022)

Microtubule plus tips: A dynamic route to chromosomal instability
por: Stolz, Ailine, et al.
Publicado: (2014)

Sequential Water and Headgroup Merger: Membrane Poration Paths and Energetics from MD Simulations
por: Bubnis, Greg, et al.
Publicado: (2020)

The energetics of rapid cellular mechanotransduction
por: Young, Michael N., et al.
Publicado: (2023)

Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy
por: Drake, Joshua C., et al.
Publicado: (2021)

Elastic and Irreversible Bending of Tree and Shrub Branches Under Cantilever Loads
por: Ray, Peter M., et al.
Publicado: (2019)

The plus ends of stable microtubules are the exclusive nucleating structures for microtubules in the axon
Publicado: (1992)

Tight bending of the Ndc80 complex provides intrinsic regulation of its binding to microtubules
por: Scarborough, Emily Anne, et al.
Publicado: (2019)

NOD is a plus end–directed motor that binds EB1 via a new microtubule tip localization sequence
por: Ye, Anna A., et al.
Publicado: (2018)

Dynamic Localization of CLIP-170 to Microtubule Plus Ends Is Coupled to Microtubule Assembly
por: Diamantopoulos, Georgios S., et al.
Publicado: (1999)

Novel Arabidopsis microtubule-associated proteins track growing microtubule plus ends
por: Wong, Jeh Haur, et al.
Publicado: (2017)

MipZ caps the plus-end of FtsZ polymers to promote their rapid disassembly
por: Corrales-Guerrero, Laura, et al.
Publicado: (2022)

Multivalency ensures persistence of a +TIP body at specialized microtubule ends
por: Meier, Sandro M., et al.
Publicado: (2022)

GTP-tubulin loves microtubule plus ends but marries the minus ends
por: Wordeman, Linda
Publicado: (2019)

Microtubule plus-end tracking proteins in neuronal development
por: van de Willige, Dieudonnée, et al.
Publicado: (2016)

BEND3 safeguards pluripotency by repressing differentiation-associated genes
por: Kurniawan, Fredy, et al.
Publicado: (2022)

Information flow, gating, and energetics in dimeric molecular motors
por: Takaki, Ryota, et al.
Publicado: (2022)

Forces and energetics of the canonical tetrameric cation channel gating
por: Scheuring, Simon
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_j9cb72nngvumc8hn807htdvkc3