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Piperine Attenuates Lithocholic Acid-Stimulated Interleukin-8 by Suppressing Src/EGFR and Reactive Oxygen Species in Human Colorectal Cancer Cells

Piperine, a natural alkaloidal pungent product present in pepper plants, possesses the properties of anti-inflammatory and anti-metastasis. Lithocholic acid is a monohydroxy-5beta-cholanic acid with an alpha-hydroxy substituent at position 3; it is a secondary bile acid that plays a pivotal role in...

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Detalles Bibliográficos
Autores principales: Li, Shinan, Nguyen, Thi Thinh, Ung, Trong Thuan, Sah, Dhiraj Kumar, Park, Seon Young, Lakshmanan, Vinoth-Kumar, Jung, Young Do
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944659/
https://www.ncbi.nlm.nih.gov/pubmed/35326180
http://dx.doi.org/10.3390/antiox11030530