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N-Acetylcysteine Inhibits Platelet Function through the Regeneration of the Non-Oxidative Form of Albumin

N-acetylcysteine (NAC) is able to break down protein disulfides, generating free thiols. This mechanism occurs on mixed disulfides of albumin (HSA) to form mercaptoalbumin (HMA), the main antioxidant species in the plasma. Circulating HSA exists in two main forms: the reduced form (HMA), and the oxi...

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Detalles Bibliográficos
Autores principales: Eligini, Sonia, Porro, Benedetta, Aldini, Giancarlo, Colli, Susanna, Banfi, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944739/
https://www.ncbi.nlm.nih.gov/pubmed/35326096
http://dx.doi.org/10.3390/antiox11030445