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Novel Antimicrobial Peptides Designed Using a Recurrent Neural Network Reduce Mortality in Experimental Sepsis

The search and development of new antibiotics is relevant due to widespread antibiotic resistance. One of the promising strategies is the de novo design of novel antimicrobial peptides. The amino acid sequences of 198 novel peptides were obtained using a generative long short-term memory recurrent n...

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Detalles Bibliográficos
Autores principales: Bolatchiev, Albert, Baturin, Vladimir, Shchetinin, Evgeny, Bolatchieva, Elizaveta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944797/
https://www.ncbi.nlm.nih.gov/pubmed/35326874
http://dx.doi.org/10.3390/antibiotics11030411