Cargando…
Novel Antimicrobial Peptides Designed Using a Recurrent Neural Network Reduce Mortality in Experimental Sepsis
The search and development of new antibiotics is relevant due to widespread antibiotic resistance. One of the promising strategies is the de novo design of novel antimicrobial peptides. The amino acid sequences of 198 novel peptides were obtained using a generative long short-term memory recurrent n...
Autores principales: | Bolatchiev, Albert, Baturin, Vladimir, Shchetinin, Evgeny, Bolatchieva, Elizaveta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944797/ https://www.ncbi.nlm.nih.gov/pubmed/35326874 http://dx.doi.org/10.3390/antibiotics11030411 |
Ejemplares similares
-
Andrographolide and 4-Phenylbutyric Acid Administration Increase the Expression of Antimicrobial Peptides Beta-Defensin-1 and Cathelicidin and Reduce Mortality in Murine Sepsis
por: Bolatchiev, Albert, et al.
Publicado: (2022) -
Potential and Possible Therapeutic Effects of Melatonin on SARS-CoV-2 Infection
por: Shchetinin, Evgeny, et al.
Publicado: (2022) -
Antimicrobial Peptides Epinecidin-1 and Beta-Defesin-3 Are Effective against a Broad Spectrum of Antibiotic-Resistant Bacterial Isolates and Increase Survival Rate in Experimental Sepsis
por: Bolatchiev, Albert
Publicado: (2022) -
Antibacterial activity of human defensins against Staphylococcus aureus and Escherichia coli
por: Bolatchiev, Albert
Publicado: (2020) -
Antimicrobial Peptides in Human Sepsis
por: Martin, Lukas, et al.
Publicado: (2015)