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Highly Specific Monoclonal Antibody Targeting the Botulinum Neurotoxin Type E Exposed SNAP-25 Neoepitope

Botulinum neurotoxin type E (BoNT/E), the fastest acting toxin of all BoNTs, cleaves the 25 kDa synaptosomal-associated protein (SNAP-25) in motor neurons, leading to flaccid paralysis. The specific detection and quantification of the BoNT/E-cleaved SNAP-25 neoepitope can facilitate the development...

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Detalles Bibliográficos
Autores principales: Mechaly, Adva, Diamant, Eran, Alcalay, Ron, Ben David, Alon, Dor, Eyal, Torgeman, Amram, Barnea, Ada, Girshengorn, Meni, Levin, Lilach, Epstein, Eyal, Tennenhouse, Ariel, Fleishman, Sarel J., Zichel, Ran, Mazor, Ohad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944829/
https://www.ncbi.nlm.nih.gov/pubmed/35323195
http://dx.doi.org/10.3390/antib11010021