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Screening Repurposed Antiviral Small Molecules as Antimycobacterial Compounds by a Lux-Based phoP Promoter-Reporter Platform

The emergence of multidrug-resistant strains and hyper-virulent strains of Mycobacterium tuberculosis are big therapeutic challenges for tuberculosis (TB) control. Repurposing bioactive small-molecule compounds has recently become a new therapeutic approach against TB. This study aimed to identify n...

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Detalles Bibliográficos
Autores principales: Zhu, Li, Lee, Annie Wing-Tung, Wu, Kelvin Ka-Lok, Gao, Peng, Tam, Kingsley King-Gee, Rajwani, Rahim, Chaburte, Galata Chala, Ng, Timothy Ting-Leung, Chan, Chloe Toi-Mei, Lao, Hiu Yin, Yam, Wing Cheong, Kao, Richard Yi-Tsun, Siu, Gilman Kit Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944841/
https://www.ncbi.nlm.nih.gov/pubmed/35326832
http://dx.doi.org/10.3390/antibiotics11030369