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Triglyceride breakdown from lipid droplets regulates the inflammatory response in macrophages

In response to inflammatory activation by pathogens, macrophages accumulate triglycerides in intracellular lipid droplets. The mechanisms underlying triglyceride accumulation and its exact role in the inflammatory response of macrophages are not fully understood. Here, we aim to further elucidate th...

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Detalles Bibliográficos
Autores principales: van Dierendonck, Xanthe A. M. H., Vrieling, Frank, Smeehuijzen, Lisa, Deng, Lei, Boogaard, Joline P., Croes, Cresci-Anne, Temmerman, Lieve, Wetzels, Suzan, Biessen, Erik, Kersten, Sander, Stienstra, Rinke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944848/
https://www.ncbi.nlm.nih.gov/pubmed/35302892
http://dx.doi.org/10.1073/pnas.2114739119