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AhR promotes phosphorylation of ARNT isoform 1 in human T cell malignancies as a switch for optimal AhR activity

The aryl hydrocarbon receptor nuclear translocator (ARNT) is a transcription factor present in immune cells as a long and short isoform, referred to as isoforms 1 and 3, respectively. However, investigation into potential ARNT isoform–specific immune functions is lacking despite the well-established...

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Detalles Bibliográficos
Autores principales: Bourner, Luke A., Muro, Israel, Cooper, Amy M., Choudhury, Barun K., Bailey, Aaron O., Russell, William K., Khanipov, Kamil, Golovko, George, Wright, Casey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944900/
https://www.ncbi.nlm.nih.gov/pubmed/35290121
http://dx.doi.org/10.1073/pnas.2114336119