Lysosomal inhibition sensitizes TMEM16A-expressing cancer cells to chemotherapy

Squamous cell carcinoma of the head and neck (SCCHN) is a devastating disease that continues to have low cure rates despite the recent advances in therapies. Cisplatin is the most used chemotherapy agent, and treatment failure is largely driven by resistance to this drug. Amplification of chromosoma...

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Detalles Bibliográficos
Autores principales: Vyas, Avani, Gomez-Casal, Roberto, Cruz-Rangel, Silvia, Villanueva, Hugo, Sikora, Andrew G., Rajagopalan, Pavithra, Basu, Devraj, Pacheco, Jonathan, Hammond, Gerald R. V., Kiselyov, Kirill, Duvvuri, Umamaheswar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944912/
https://www.ncbi.nlm.nih.gov/pubmed/35286200
http://dx.doi.org/10.1073/pnas.2100670119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944912/
https://www.ncbi.nlm.nih.gov/pubmed/35286200
http://dx.doi.org/10.1073/pnas.2100670119

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