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Diffusion and distal linkages govern interchromosomal dynamics during meiotic prophase

The pairing of homologous chromosomes (homologs) in meiosis is essential for distributing the correct numbers of chromosomes into haploid gametes. In budding yeast, pairing depends on the formation of 150 to 200 Spo11-mediated double-strand breaks (DSBs) that are distributed among 16 homolog pairs,...

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Detalles Bibliográficos
Autores principales: Newman, Trent A. C., Beltran, Bruno, McGehee, James M., Elnatan, Daniel, Cahoon, Cori K., Paddy, Michael R., Chu, Daniel B., Spakowitz, Andrew J., Burgess, Sean M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944930/
https://www.ncbi.nlm.nih.gov/pubmed/35302885
http://dx.doi.org/10.1073/pnas.2115883119