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Secretin Receptor as a Target in Gastrointestinal Cancer: Expression Analysis and Ligand Development

Secretin was originally discovered as a gastrointestinal peptide that stimulates fluid secretion from the pancreas and liver and delays gastric emptying. In disease, a secretin receptor (SCTR) was found to occur as a splice variant in gastrinoma and pancreatic adenocarcinoma. Overexpression of SCTR...

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Detalles Bibliográficos
Autores principales: Klussmeier, Anja, Aurich, Stefan, Niederstadt, Lars, Wiedenmann, Bertram, Grötzinger, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944975/
https://www.ncbi.nlm.nih.gov/pubmed/35327338
http://dx.doi.org/10.3390/biomedicines10030536