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Secretin Receptor as a Target in Gastrointestinal Cancer: Expression Analysis and Ligand Development
Secretin was originally discovered as a gastrointestinal peptide that stimulates fluid secretion from the pancreas and liver and delays gastric emptying. In disease, a secretin receptor (SCTR) was found to occur as a splice variant in gastrinoma and pancreatic adenocarcinoma. Overexpression of SCTR...
Autores principales: | Klussmeier, Anja, Aurich, Stefan, Niederstadt, Lars, Wiedenmann, Bertram, Grötzinger, Carsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944975/ https://www.ncbi.nlm.nih.gov/pubmed/35327338 http://dx.doi.org/10.3390/biomedicines10030536 |
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