S-15176 Difumarate Salt Can Impair Mitochondrial Function through Inhibition of the Respiratory Complex III and Permeabilization of the Inner Mitochondrial Membrane

SIMPLE SUMMARY: The metabolic agent S-15176 difumarate salt belongs to a potent class of drugs called partial fatty acid oxidation inhibitors. The possible therapeutic effects of this agent have been widely investigated in models of oxidative damage to different tissues, but the underlying mechanism...

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Detalles Bibliográficos
Autores principales: Belosludtseva, Natalia V., Starinets, Vlada S., Semenova, Alena A., Igoshkina, Anastasia D., Dubinin, Mikhail V., Belosludtsev, Konstantin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945000/
https://www.ncbi.nlm.nih.gov/pubmed/35336754
http://dx.doi.org/10.3390/biology11030380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945000/
https://www.ncbi.nlm.nih.gov/pubmed/35336754
http://dx.doi.org/10.3390/biology11030380

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