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Interleukin-27 Regulates the Function of the Gastrointestinal Epithelial Barrier in a Human Tissue-Derived Organoid Model

SIMPLE SUMMARY: The gut is lined by a single layer of epithelial cells, creating a barrier between the contents of the gut and the underlying tissue. This barrier also controls permeability (to determine if gut contents move to the tissue) and produces proteins that help with immune responses. These...

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Detalles Bibliográficos
Autores principales: Brice, Daniel P., Murray, Graeme I., Wilson, Heather M., Porter, Ross J., Berry, Susan, Durum, Scott K., McLean, Mairi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945023/
https://www.ncbi.nlm.nih.gov/pubmed/35336801
http://dx.doi.org/10.3390/biology11030427