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Triiodothyronine (T3) Induces Limited Transcriptional and DNA Methylation Reprogramming in Human Monocytes

Thyroid hormones have immunomodulatory roles, but their effects on the transcriptome and epigenome of innate immune cell types remain unexplored. In this study, we investigate the effects of triiodothyronine (T3) on the transcriptome and methylome of human monocytes in vitro, both in resting and lip...

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Detalles Bibliográficos
Autores principales: Shepherd, Rebecca, Kim, Bowon, Saffery, Richard, Novakovic, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945024/
https://www.ncbi.nlm.nih.gov/pubmed/35327410
http://dx.doi.org/10.3390/biomedicines10030608