Intracerebroventricular Administration of Human Umbilical Cord Blood—Derived Mesenchymal Stem Cells Induces Transient Inflammation in a Transgenic Mouse Model and Patients with Alzheimer’s Disease

Previously we conducted a Phase I/IIa clinical trial in nine patients with mild to moderate Alzheimer’s disease (AD). Unexpectedly, all patients who were given injections of human-umbilical cord-blood-derived mesenchymal stem cells (hUCB-MSCs) developed fever which subsided after 24 h. Several possi...

Descripción completa

Detalles Bibliográficos
Autores principales: Myeong, Su Hyeon, Kim, Hyeongseop, Lee, Na Kyung, Hwang, Jung Won, Kim, Hee Jin, Jang, Hyemin, Choi, Soo Jin, Na, Duk L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945031/
https://www.ncbi.nlm.nih.gov/pubmed/35327365
http://dx.doi.org/10.3390/biomedicines10030563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945031/
https://www.ncbi.nlm.nih.gov/pubmed/35327365
http://dx.doi.org/10.3390/biomedicines10030563

Ejemplares similares