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Intracerebroventricular Administration of Human Umbilical Cord Blood—Derived Mesenchymal Stem Cells Induces Transient Inflammation in a Transgenic Mouse Model and Patients with Alzheimer’s Disease

Previously we conducted a Phase I/IIa clinical trial in nine patients with mild to moderate Alzheimer’s disease (AD). Unexpectedly, all patients who were given injections of human-umbilical cord-blood-derived mesenchymal stem cells (hUCB-MSCs) developed fever which subsided after 24 h. Several possi...

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Detalles Bibliográficos
Autores principales:	Myeong, Su Hyeon, Kim, Hyeongseop, Lee, Na Kyung, Hwang, Jung Won, Kim, Hee Jin, Jang, Hyemin, Choi, Soo Jin, Na, Duk L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945031/ https://www.ncbi.nlm.nih.gov/pubmed/35327365 http://dx.doi.org/10.3390/biomedicines10030563

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