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Bezafibrate Reduces Elevated Hepatic Fumarate in Insulin-Deficient Mice

Glucotoxic metabolites and pathways play a crucial role in diabetic complications, and new treatment options which improve glucotoxicity are highly warranted. In this study, we analyzed bezafibrate (BEZ) treated, streptozotocin (STZ) injected mice, which showed an improved glucose metabolism compare...

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Detalles Bibliográficos
Autores principales: Franko, Andras, Irmler, Martin, Prehn, Cornelia, Heinzmann, Silke S., Schmitt-Kopplin, Philippe, Adamski, Jerzy, Beckers, Johannes, von Kleist-Retzow, Jürgen-Christoph, Wiesner, Rudolf, Häring, Hans-Ulrich, Heni, Martin, Birkenfeld, Andreas L., de Angelis, Martin Hrabě
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945094/
https://www.ncbi.nlm.nih.gov/pubmed/35327418
http://dx.doi.org/10.3390/biomedicines10030616