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Bezafibrate Reduces Elevated Hepatic Fumarate in Insulin-Deficient Mice
Glucotoxic metabolites and pathways play a crucial role in diabetic complications, and new treatment options which improve glucotoxicity are highly warranted. In this study, we analyzed bezafibrate (BEZ) treated, streptozotocin (STZ) injected mice, which showed an improved glucose metabolism compare...
Autores principales: | Franko, Andras, Irmler, Martin, Prehn, Cornelia, Heinzmann, Silke S., Schmitt-Kopplin, Philippe, Adamski, Jerzy, Beckers, Johannes, von Kleist-Retzow, Jürgen-Christoph, Wiesner, Rudolf, Häring, Hans-Ulrich, Heni, Martin, Birkenfeld, Andreas L., de Angelis, Martin Hrabě |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945094/ https://www.ncbi.nlm.nih.gov/pubmed/35327418 http://dx.doi.org/10.3390/biomedicines10030616 |
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