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Synthesis of 3-O-Acetyl-11-keto-β-boswellic Acid (AKBA)-Derived Amides and Their Mitochondria-Targeted Antitumor Activities

[Image: see text] In this study, we synthesized a series of amide and mitochondria-targeted derivatives with 3-O-acetyl-11-keto-β-boswellic acid (AKBA) as the parent structure and an ethylenediamine moiety as the link chain. Compound 5e, a mitochondrial-targeting potential derivative, showed signifi...

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Detalles Bibliográficos
Autores principales: Li, Changhao, He, Qiaobian, Xu, Yuwen, Lou, Hongxiang, Fan, Peihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945107/
https://www.ncbi.nlm.nih.gov/pubmed/35350335
http://dx.doi.org/10.1021/acsomega.2c00203