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Frequency and Clinical Significance of Elevated IgG4 in Rheumatoid Arthritis: A Systematic Review

Immunoglobulin (Ig)G4 is a unique protein molecule and its role in autoimmune diseases remains elusive and controversial. Accumulating evidence suggests a pathogenic role of IgG4 in rheumatoid arthritis (RA). Rheumatoid factors (RF) in RA can recognize the Fc domains of IgG4 to form RF-IgG4 immune c...

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Detalles Bibliográficos
Autores principales: Sakthiswary, Rajalingham, Shaharir, Syahrul Sazliyana, Wahab, Asrul Abdul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945114/
https://www.ncbi.nlm.nih.gov/pubmed/35327360
http://dx.doi.org/10.3390/biomedicines10030558