l- to d-Amino Acid Substitution in the Immunodominant LCMV-Derived Epitope gp33 Highlights the Sensitivity of the TCR Recognition Mechanism for the MHC/Peptide Structure and Dynamics

[Image: see text] Presentation of pathogen-derived epitopes by major histocompatibility complex I (MHC-I) can lead to the activation and expansion of specific CD8(+) T cell clones, eventually resulting in the destruction of infected target cells. Altered peptide ligands (APLs), designed to elicit im...

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Detalles Bibliográficos
Autores principales: Ballabio, Federico, Broggini, Luca, Paissoni, Cristina, Han, Xiao, Peqini, Kaliroi, Sala, Benedetta Maria, Sun, Renhua, Sandalova, Tatyana, Barbiroli, Alberto, Achour, Adnane, Pellegrino, Sara, Ricagno, Stefano, Camilloni, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945122/
https://www.ncbi.nlm.nih.gov/pubmed/35350306
http://dx.doi.org/10.1021/acsomega.1c06964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945122/
https://www.ncbi.nlm.nih.gov/pubmed/35350306
http://dx.doi.org/10.1021/acsomega.1c06964

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