Design, Synthesis, and Bioevaluation of Indole Core Containing 2-Arylidine Derivatives of Thiazolopyrimidine as Multitarget Inhibitors of Cholinesterases and Monoamine Oxidase A/B for the Treatment of Alzheimer Disease

[Image: see text] In continuation of our previous study to identify multitarget inhibitors of cholinesterases (ChEs) and monoamine oxidase (MAOs) isoforms, we synthesized and evaluated 2-arylidine derivatives of thiazolopyrimidine for the treatment of Alzheimer disease. Three series of compounds wit...

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Detalles Bibliográficos
Autores principales: Shahid Nadeem, Muhammad, Azam Khan, Jalaluddin, Kazmi, Imran, Rashid, Umer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945123/
https://www.ncbi.nlm.nih.gov/pubmed/35350344
http://dx.doi.org/10.1021/acsomega.1c06344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945123/
https://www.ncbi.nlm.nih.gov/pubmed/35350344
http://dx.doi.org/10.1021/acsomega.1c06344

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