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SUCNR1 Mediates the Priming Step of the Inflammasome in Intestinal Epithelial Cells: Relevance in Ulcerative Colitis

Intestinal epithelial cells (IECs) constitute a defensive physical barrier in mucosal tissues and their disruption is involved in the etiopathogenesis of several inflammatory pathologies, such as Ulcerative Colitis (UC). Recently, the succinate receptor SUCNR1 was associated with the activation of i...

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Detalles Bibliográficos
Autores principales: Bauset, Cristina, Lis-Lopez, Lluis, Coll, Sandra, Gisbert-Ferrándiz, Laura, Macias-Ceja, Dulce C., Seco-Cervera, Marta, Navarro, Francisco, Esplugues, Juan V., Calatayud, Sara, Ortiz-Masia, Dolores, Barrachina, Maria D., Cosín-Roger, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945150/
https://www.ncbi.nlm.nih.gov/pubmed/35327334
http://dx.doi.org/10.3390/biomedicines10030532