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SUCNR1 Mediates the Priming Step of the Inflammasome in Intestinal Epithelial Cells: Relevance in Ulcerative Colitis
Intestinal epithelial cells (IECs) constitute a defensive physical barrier in mucosal tissues and their disruption is involved in the etiopathogenesis of several inflammatory pathologies, such as Ulcerative Colitis (UC). Recently, the succinate receptor SUCNR1 was associated with the activation of i...
Autores principales: | Bauset, Cristina, Lis-Lopez, Lluis, Coll, Sandra, Gisbert-Ferrándiz, Laura, Macias-Ceja, Dulce C., Seco-Cervera, Marta, Navarro, Francisco, Esplugues, Juan V., Calatayud, Sara, Ortiz-Masia, Dolores, Barrachina, Maria D., Cosín-Roger, Jesús |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945150/ https://www.ncbi.nlm.nih.gov/pubmed/35327334 http://dx.doi.org/10.3390/biomedicines10030532 |
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