t(4;12)(q12;p13) ETV6-rearranged AML without eosinophilia does not involve PDGFRA: relevance for imatinib insensitivity

Acute myeloid leukemia (AML) with t(4;12)(q12;p13) translocation is rare and often associated with an aggressive clinical course and poor prognosis. Previous reports based on fluorescence in situ hybridization (FISH) analysis have suggested that ETV6::PDGFRA fusions are present in these patients, de...

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Detalles Bibliográficos
Autores principales: Mueller, Sarah B., Dal Cin, Paola, Le, Long P., Dias-Santagata, Dora, Lennerz, Jochen K., Iafrate, A. John, Marble, Hetal Desai, Brunner, Andrew M., Weinstock, Matthew J., Luskin, Marlise R., De Angelo, Daniel J., Stone, Richard M., Nardi, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Myeloid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945303/
https://www.ncbi.nlm.nih.gov/pubmed/34587239
http://dx.doi.org/10.1182/bloodadvances.2021005280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945303/
https://www.ncbi.nlm.nih.gov/pubmed/34587239
http://dx.doi.org/10.1182/bloodadvances.2021005280

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