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Epithelial–Fibroblast Crosstalk Protects against Acidosis-Induced Inflammatory and Fibrotic Alterations

Pathogenesis of chronic kidney disease (CKD) is accompanied by extracellular acidosis inflammation, fibrosis and epithelial-to-mesenchymal transition (EMT). The aim of this study was to assess the influence of acidosis on tubule epithelial cells (NRK-52E) and fibroblasts (NRK-49F) in dependence of c...

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Detalles Bibliográficos
Autores principales: Schulz, Marie-Christin, Voß, Linda, Schwerdt, Gerald, Gekle, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945333/
https://www.ncbi.nlm.nih.gov/pubmed/35327483
http://dx.doi.org/10.3390/biomedicines10030681