Activation of Voltage-Gated Na(+) Current by GV-58, a Known Activator of Ca(V) Channels

GV-58 ((2R)-2-[(6-{[(5-methylthiophen-2-yl)methyl]amino}-9-propyl-9H-purin-2-yl)amino]butan-1-ol) is recognized to be an activator of N- and P/Q-type Ca(2+) currents. However, its modulatory actions on other types of ionic currents in electrically excitable cells remain largely unanswered. This stud...

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Detalles Bibliográficos
Autores principales: Cho, Hsin-Yen, Chen, Pei-Chun, Chuang, Tzu-Hsien, Yu, Meng-Cheng, Wu, Sheng-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945347/
https://www.ncbi.nlm.nih.gov/pubmed/35327523
http://dx.doi.org/10.3390/biomedicines10030721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945347/
https://www.ncbi.nlm.nih.gov/pubmed/35327523
http://dx.doi.org/10.3390/biomedicines10030721

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