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A Single-Molecule View at Nanoparticle Targeting Selectivity: Correlating Ligand Functionality and Cell Receptor Density

[Image: see text] Antibody-functionalized nanoparticles (NPs) are commonly used to increase the targeting selectivity toward cells of interest. At a molecular level, the number of functional antibodies on the NP surface and the density of receptors on the target cell determine the targeting interact...

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Detalles Bibliográficos
Autores principales: Woythe, Laura, Madhikar, Pranav, Feiner-Gracia, Natalia, Storm, Cornelis, Albertazzi, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945370/
https://www.ncbi.nlm.nih.gov/pubmed/35274534
http://dx.doi.org/10.1021/acsnano.1c08277