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Population pharmacokinetic modeling of factor concentrates in hemophilia: an overview and evaluation of best practice
The accuracy of pharmacokinetic (PK)-guided dosing depends on the clinical and laboratory data used to construct a population PK model, as well as the patient’s individual PK profile. This review provides a detailed overview of data used for published population PK models for factor VIII (FVIII) and...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Hematology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945640/ https://www.ncbi.nlm.nih.gov/pubmed/34496017 http://dx.doi.org/10.1182/bloodadvances.2021005096 |