Cre/LoxP Genetic Recombination Sustains Cartilage Anabolic Factor Expression in Hyaluronan Encapsulated MSCs Alleviates Intervertebral Disc Degeneration

(1) Background: Inexplicable low back and neck pain frequently results from spinal disc degeneration with an imbalanced intervertebral disc (IVD) cell homeostasis. We hypothesize that introducing MSC expressing a sustained cartilage-anabolic factor in the IVD may stimulate the mucoid materials secre...

Descripción completa

Detalles Bibliográficos
Autores principales: Chan, Long-Yi, Chang, Cheng-Chung, Lai, Po-Liang, Maeda, Tomoji, Hsu, Horng-Chaung, Lin, Chin-Yu, Kuo, Shu-Jui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945655/
https://www.ncbi.nlm.nih.gov/pubmed/35327357
http://dx.doi.org/10.3390/biomedicines10030555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945655/
https://www.ncbi.nlm.nih.gov/pubmed/35327357
http://dx.doi.org/10.3390/biomedicines10030555

Ejemplares similares