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CNN-XG: A Hybrid Framework for sgRNA On-Target Prediction

As the third generation gene editing technology, Crispr/Cas9 has a wide range of applications. The success of Crispr depends on the editing of the target gene via a functional complex of sgRNA and Cas9 proteins. Therefore, highly specific and high on-target cleavage efficiency sgRNA can make this pr...

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Detalles Bibliográficos
Autores principales: Li, Bohao, Ai, Dongmei, Liu, Xiuqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945678/
https://www.ncbi.nlm.nih.gov/pubmed/35327601
http://dx.doi.org/10.3390/biom12030409