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CNN-XG: A Hybrid Framework for sgRNA On-Target Prediction
As the third generation gene editing technology, Crispr/Cas9 has a wide range of applications. The success of Crispr depends on the editing of the target gene via a functional complex of sgRNA and Cas9 proteins. Therefore, highly specific and high on-target cleavage efficiency sgRNA can make this pr...
Autores principales: | Li, Bohao, Ai, Dongmei, Liu, Xiuqin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945678/ https://www.ncbi.nlm.nih.gov/pubmed/35327601 http://dx.doi.org/10.3390/biom12030409 |
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