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NF-κB Signaling and Inflammation—Drug Repurposing to Treat Inflammatory Disorders?

SIMPLE SUMMARY: Since its first description 35 years ago, the transcription factor NF-κB (nuclear factor κ-light-chain-enhancer of activated B cells) has been shown to be a key mediator of immune cell responses to inflammatory mediators, oxidative stress and genotoxic injury. Dysregulated NF-κB sign...

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Detalles Bibliográficos
Autores principales: Roberti, Annabell, Chaffey, Laura Elizabeth, Greaves, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945680/
https://www.ncbi.nlm.nih.gov/pubmed/35336746
http://dx.doi.org/10.3390/biology11030372