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NF-κB Signaling and Inflammation—Drug Repurposing to Treat Inflammatory Disorders?
SIMPLE SUMMARY: Since its first description 35 years ago, the transcription factor NF-κB (nuclear factor κ-light-chain-enhancer of activated B cells) has been shown to be a key mediator of immune cell responses to inflammatory mediators, oxidative stress and genotoxic injury. Dysregulated NF-κB sign...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945680/ https://www.ncbi.nlm.nih.gov/pubmed/35336746 http://dx.doi.org/10.3390/biology11030372 |