Early-Onset Glaucoma in egl1 Mice Homozygous for Pitx2 Mutation

Mutations in PITX2 cause Axenfeld–Rieger syndrome, with congenital glaucoma as an ocular feature. The egl1 mouse strain carries a chemically induced Pitx2 mutation and develops early-onset glaucoma. In this study, we characterized the glaucomatous features in egl1 mice. The eyes of egl1 and C57BL/6J...

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Detalles Bibliográficos
Autores principales: Kodati, Bindu, Merchant, Shawn A., Millar, J. Cameron, Liu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945683/
https://www.ncbi.nlm.nih.gov/pubmed/35327318
http://dx.doi.org/10.3390/biomedicines10030516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945683/
https://www.ncbi.nlm.nih.gov/pubmed/35327318
http://dx.doi.org/10.3390/biomedicines10030516

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