Drug-Targeted Genomes: Mutability of Ion Channels and GPCRs

Mutations of ion channels and G-protein-coupled receptors (GPCRs) are not uncommon and can lead to cardiovascular diseases. Given previously reported multiple factors associated with high mutation rates, we sorted the relative mutability of multiple human genes by (i) proximity to telomeres and/or (...

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Detalles Bibliográficos
Autores principales: Raines, Regan, McKnight, Ian, White, Hunter, Legg, Kaitlyn, Lee, Chan, Li, Wei, Lee, Peter H. U., Shim, Joon W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945769/
https://www.ncbi.nlm.nih.gov/pubmed/35327396
http://dx.doi.org/10.3390/biomedicines10030594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945769/
https://www.ncbi.nlm.nih.gov/pubmed/35327396
http://dx.doi.org/10.3390/biomedicines10030594

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