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Drug-Targeted Genomes: Mutability of Ion Channels and GPCRs
Mutations of ion channels and G-protein-coupled receptors (GPCRs) are not uncommon and can lead to cardiovascular diseases. Given previously reported multiple factors associated with high mutation rates, we sorted the relative mutability of multiple human genes by (i) proximity to telomeres and/or (...
Autores principales: | Raines, Regan, McKnight, Ian, White, Hunter, Legg, Kaitlyn, Lee, Chan, Li, Wei, Lee, Peter H. U., Shim, Joon W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945769/ https://www.ncbi.nlm.nih.gov/pubmed/35327396 http://dx.doi.org/10.3390/biomedicines10030594 |
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