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Leelamine Modulates STAT5 Pathway Causing Both Autophagy and Apoptosis in Chronic Myelogenous Leukemia Cells

SIMPLE SUMMARY: Autophagy is a cellular mechanism that is essential for removing misfolded proteins and damaged organelles. Moreover, the aberrant activation of signal transducer and activator of transcription 5 (STAT5), which can regulate cellular survival and homeostasis, has been often observed i...

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Detalles Bibliográficos
Autores principales: Jung, Young Yun, Um, Jae-Young, Chinnathambi, Arunachalam, Govindasamy, Chandramohan, Sethi, Gautam, Ahn, Kwang Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945775/
https://www.ncbi.nlm.nih.gov/pubmed/35336740
http://dx.doi.org/10.3390/biology11030366